Toxicological studies of a leachable stabilizer Di-n-butyltin dilaurate (DBTL) were undertaken. In general, toxicity decreases as the number of ... dibutyltin oxide, dibutyltin dilaurate, dibutyltin diacetate, or tetrabutyltin on the back of the hands of volunteers did not cause irritation. Dibutyltin dilaurate Revision Date 23-Jan-2018 Danger Hazard Statements Causes severe skin burns and eye damage May cause respiratory irritation May cause an allergic skin reaction May cause drowsiness or dizziness Suspected of causing genetic defects May damage fertility. ... , dibutyltin maleate, dibutyltin oxide, and dibutyltin dilaurate were teratogenic in rats when administered orally. 4. EC Number: 221-434-9. Dibutyltin dilaurate (CAS PEL 0.1 mg/m3 77-58-7) US. CAS numbers identify the chemical, but not its concentration or specific mixture. SC-239690 - Dibutyltin dilaurate Revision date 03-Aug-2020 ATEmix (dermal) 630 mg/kg ATEmix (inhalation-dust/mist)0.5 mg/l 12. . Serious eye damage/eye irritation Causes serious eye irritation. Dibutyltin dilaurate for synthesis. - Find MSDS or SDS, a COA, data sheets and more information. Foreign name: T-12. Always wear rubber-gloves and work under a fume hood. Uses of Dibutyltin dilaurate: Dibutyltin compounds are used mainly as additives in PVC plastic as a stabiliser. Dibutyltin dilaurate - (77-58-7) 2,000.00, Rat - Category: 4 No data available No data available No data available No data available Note: When no route specific LD50 data is available for an acute toxin, the converted acute toxicity point estimate was used in the calculation of the product's ATE (Acute Toxicity Estimate). Dibutyltin dilaurate (DBTDL) is an organotin compound that is used as a catalyst. Dibutyltin dilaurate 77-58-7 Skin Corr/Irrit 1 Eye Damage/Irrit 1 Skin Sens 1 Mutagenicity 2 Reproductive Tox 1B STOT-SE 1 Aquatic Acute 1 Aquatic Chronic 1 0-10 Other ingredients are not classified as health and/or environmental hazards, and/or are present below cut-off/concentration limits. Dibutyltin dilaurate is an organic tin additives, and can be soluble in benzene, toluene, carbon tetrachloride, ethyl acetate, chloroform, acetone, petroleum ether and other organic solvents and all industrial plasticizers, but insoluble in water. ECOLOGICAL INFORMATION _____ Ecotoxicity Very toxic to aquatic life with long lasting effects Chemical name Algae/aquatic plants Fish Toxicity to Microorganisms Crustacea Dibutyltin dilaurate … STOT - single exposure Thymus. 4.11 Transport UN 2922 4.12 Fire Potential Combustible when exposed to heat or flame; reacts with oxidizers. Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 3.3 mg/l Exposure time: 96 h dibutyltin dilaurate : Toxicity to fish : LC50 (Fish): 3.1 mg/l Exposure time: 96 h Toxicity to daphnia and other aquatic invertebrates : EC50 (Daphnia (water flea)): 1 mg/l Exposure time: 48 h Toxicity to algae Carcinogenicity, category 1B … Breakdown of all 1500 C&L notifications submitted to ECHA dibutyltin dilaurate; dibutyl [bis (dodecanoyloxy)] stannane. Respiratory or skin sensitisation Skin sensitisation: Not classified based on available information. Developmental toxicity studies on butyltins suggest that the … NIOSH: Pocket Guide to Chemical Hazards Components Type Value Dibutyltin dilaurate (CAS TWA 0.1 mg/m3 77-58-7) Biological limit values … Hazardous Substances Data Bank (HSDB) Polyurethane foam catalyst. Repeat exposure: No data available. From: Handbook on the Toxicology of Metals (Fourth Edition), 2015 Acute Toxicity, Inhalation, category 3 H331 Toxic if inhaled. Dibutyltin dilaurate is a chemically active, moderately toxic organic tin compound, with a specific gravity of 1.05 g/cm 3. SAFETY DATA SHEET According to JIS Z 7253:2019 Version 5.02 Revision Date 14-Jan-2021 Section 1: PRODUCT AND COMPANY IDENTIFICATION Product name Dibutyltin(IV) Dilaurate Product code 040-17172,044-17175 Manufacturer FUJIFILM Wako Pure Chemical Corporation 1-2 Doshomachi 3-Chome Chemicals known to cause reproductive toxicity for males: ... 77-58-7 dibutyltin dilaurate . Toxicity Profile for Dibutyltin dilaurate (1989) Dibutyltin dilaurate was a skin and eye irritant in rabbits. ACUTE/CHRONIC HAZARDS: This compound may cause skin irritation on contact. Asthmatic-type symptoms may develop immediately or up to several hours later. For acute toxicity to red killifish, Oryzias latipes, dibutyltin maleate is less toxic than dibutyltin oxide, diacetate and dilaurate. Dibutyltin dilaurate is an organotin compound. The Sn-S bond is the reactive component. Ecological Information Ecotoxicity: For dibutyltin dilaurate, EC50 Daphnia is 0.463 mg/l. ( 4, 6) Compound Type. LD50 Rat 2071 mg/kg Skin corrosion/irritation Causes severe skin burns and eye damage. EUH208 Contains dibutyltin dilaurate. Toluene is a central nervous system depressant and irritant of the respiratory tract and mucous membranes. (NTP, 1992) DIBUTYLTIN DILAURATE is strongly reactive with many other groups. Chemicals known to cause reproductive toxicity for females: None of the ingredients is listed. American Elements can produce materials to custom specifications by request, in addition to custom compositions for commercial and research applications and new proprietary technologies. In terms of its structure, the molecule consists of two laurate groups attached to a dibutyltin (IV) center.The molecular geometry at tin is tetrahedral. ACGIH Threshold Limit Values Components Type Value Dibutyltin dilaurate (CAS STEL 0.2 mg/m3 77-58-7) TWA 0.1 mg/m3 US. A plastic stabilizer dibutyltin dilaurate induces subchronic neurotoxicity in rats. dibutyltin dilaurate: Acute oral toxicity : LD50 Oral (Rat): 2,071 mg/kg Skin corrosion/irritation Causes mild skin irritation. 1,2-Ethylenediamine 107-15-3 0.1 - <1% # This substance has workplace exposure limit(s). Inorganic and diorganic tin compounds, e.g., dibutyltin diacetate, dilaurate, and di (2-ethylhexylanoate), catalyze the glycol- isocyanate reaction as well as the urethane condensation step and enable the preparation of foams in one step in a … dibutyltin dilaurate: a coccidiostat used in commercial poultry. (1) Carbon Black 1333-86-4 0.1 - <1% # This substance has workplace exposure limit(s). 631.6. Acute Tox. 3 H301 Toxic if swallowed. Acute Tox. 3 H331 Toxic if inhaled. Repr. 2 H361 Suspected of damaging fertility or the unborn child. Skin Irrit. 2 H315 Causes skin irritation. Eye Irrit. 2A H319 Causes serious eye irritation. STOT SE 3 H335 May cause respiratory irritation. 1. United States Toxic Substances Control Act (TSCA) Inventory: Listed. Serious eye damage/eye irritation Causes serious eye irritation. Aspiration hazard : May be fatal if swallowed and enters airways. Ecological Information Ecotoxicity: For dibutyltin dilaurate, EC50 Daphnia is 0.463 mg/l. Dibutyltin dilaurate is a toxic compound. Always wear rubber-gloves and work under a fume hood. Waste organics should be collected in a suitable marked container and properly disposed of in the organic laboratory. 6.3.2 Avoid using glassware with chips or sharp edges. Never pipette by mouth. EC Inventory: Listed. Employers are obligated to minimize worker exposure to these agents as far as possible, and must arrange for medical surveillance of workers exposed to these substances. EC Name: Tributyl (lauroyloxy)stannane. ECOLOGICAL INFORMATION It is a colourless oily liquid. Dibutyltin Dilaurate iis one of numerous organo-metallic compounds sold by American Elements under the trade name AE Organo-Metallics™ for usessuch as catalysis. Insoluble in water. SC-239690 - Dibutyltin dilaurate Revision date 03-Aug-2020 ATEmix (dermal) 630 mg/kg ATEmix (inhalation-dust/mist)0.5 mg/l 12. : 77-58-7 1.2 Relevant identified uses of the substanceor mixtureand … dibutyl tin laurate. Incompatible with acids and bases. Reproductive toxicity Category 1B Specific target organ toxicity (repeated exposure) Category 2 2.2. Allergic effects Flammable Liquid, category 3 H226 Flammable liquid and vapour. Dibutyltin dilaurate (DBTL; CAS No. DIBUTYLTIN DILAURATE: ICSC: 1171: Di-n-butyltin dilaurate Dibutylbis((1-oxododecyl)-oxy) stannane Dibutylbis(lauroyloxy)tin: May 2018: CAS #: 77-58-7: UN #: 3146 EC Number: 201-039-8 ACUTE HAZARDS PREVENTION FIRE FIGHTING; FIRE & EXPLOSION: Combustible. Belongs to the Following Reactive Group (s) Dibutyltin dilaurate: Dibutyltin dilaurate: 77-58-7: 201-039-8: European Inventory of Existing Commercial Chemical Substances (EINECS) Listed. ... , dibutyltin maleate, dibutyltin oxide, and dibutyltin dilaurate were teratogenic in rats when administered orally. Notes. Dibutyltin dilaurate: CAS Registry Number: Chemical Abstracts Service Registry Number is a unique identifier for a chemical and its synonyms. Unknown acute toxicity 20% of the mixture consists of ingredient(s) of unknown toxicity The following values are calculated based on chapter 3.1 of the GHS … Component Compounds. H373 (21.18%): Causes damage to organs through prolonged or repeated exposure [ Warning Specific target organ toxicity, repeated exposure] H412 (19.44%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard] Dibutyltin Dilaurate (77-58-7) LD50 oral rat 2071 mg/kg body weight (Rat; Equivalent or similar to OECD 401; Experimental value) LD50 dermal rat > 2000 mg/kg body weight (Rat; Experimental value; OECD 402: Acute Dermal Toxicity) ATE US (oral) 2071.000 mg/kg body weight palmitic acid (57-10-3) LD50 oral rat > … Dibutyltin dilaurate contains 18.96% Sn, and is insoluble in water but soluble in organic solvent. STOT, single exposure, category 3, RTI H335 May cause respiratory irritation. Germ Cell Mutagenicity, category 1B H340-1B May cause genetic defects. Respiratory or skin sensitisation Skin sensitisation: Not classified based on available information. Developmental toxicity of dibutyltin dichloride in cynomolgus monkeys. Restriction (s) Physical form. Reproductive Toxicity: Dibutyltin dilaurate may damage fertility or the unborn child. Acute Toxicity, Inhalation, category 4 H332 Harmful if inhaled. TIB KAT 218 Dibutyltin dilaurate (DBTL) TIB KAT P 216 DOTL on Silica Carrier TIB KAT 220 Monobutyltin tris(2-ethylhexanoate) / MBTO ... TIB KAT 216 low toxicity, standard catalyst for XPE pipes TIB KAT 218 multi-purpose catalyst TIB KAT 223 low toxicity, excellent for 1 K MS silyl NO open flames. Decomposition Products: Thermal decomposition may produce toxic oxides and fumes of the components of this product and other potentially toxic fumes. NIOSH-Ca (National Institute for Occupational Safety and Health) 60676-86-0 Silica, fused . * All concentrations are percent by weight unless … Safety Profile Category 1 H400: Very toxic to aquatic life. These effects were accompanied by a decrease in the specific activities of several microsomal enzymes. Developmental toxicity of dibutyltin dichloride in cynomolgus monkeys. Material Safety Data Sheet or SDS for Dibutyltin dilaurate 820421 from MilliporeSigma for download or viewing in the browser. 12. Impurity 1. SYMPTOMS: Symptoms associated with this compound include primary skin irritation, nausea, headache, muscular weakness and paralysis. Dibutyltin compounds can be hydrolyzed to form dibutyltin oxide (DBTO); however, because the rate at which this Acute Toxicity, Inhalation, category 4 Hazardous to the aquatic environment, Chronic, category 3 Carcinogenicity, category 1B Flammable Liquid, category 3 Germ Cell Mutagenicity, category 1B Page 1 / 11. dibutyltin dilaurate 000077-58-7 0.25 – 2.5 T;N 21-25-36/38-50/53 - Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment 4.1 Eye contact: - Rince immediately with lots of water - Consult a doctor 4.2 Skin contact: - Wash immediately with lots of water - If irritation persists consult a … Dibutyltin dilaurate (CAS PEL 0.1 mg/m3 77-58-7) US. ... 77-58-7 dibutyltin dilaurate 2.28 mg/l No information 2 mg/l. Substance Description. Effects of DBTL after 15 days oral exposure to rats were studied on brain and liver enzyme activities. Specific target organ toxicity (repeated exposure) : May cause damage to organs through prolonged or repeated exposure. Fire Hazard Dibutyltin dilaurate is combustible. Specific Target Organ Toxicity: Single exposure: Dibutyltin dilaurate causes damage to organs (immune system). Incompatible with acids and bases. The first commercially successful stabilizers were dibutyltin dilaurate (4), dibutyltin maleate (5), and dibutyltin methyl maleate (6). Name. A significant decrease in body weight gain of DBTL exposed rats were observed. 77-58-7) is a moderately toxic organotin compound that is widely used in the processing of soft transparent polyvinyl chloride products, light polyurethane foam plastic composites, and the chloroethylene copolymers (Gooch, 2011), which has been detected in many Chinese rivers (An et al., 2013, Gao et al., 2015, Jiang, 2001). 12. Section 11: Toxicological Information Toxicity Data for ADDOCAT 201 40P Toxicity Note: No data available for this product. Alias: dibutyltin dilaurate, polyurethane catalyst T-12, organotin catalyst T12, organotin-T12, catalyst T-12, Dabco T-12, Niax D-22, Kosmos 19, PC CAT T-12, Addocat 201, organotin T-12, dibutyltin dilaurate, organotin stabilizer. Organometallics are good reducing agents and therefore incompatible with oxidizing agents. Mass poisoning in cattle, palm doves and mink caused by the coccidiostat dibutyltin dilaurate. ghs classification:dibutyltin dilaurate acute toxicity,oral (category 3) acute toxicity,inhalation (category 1) acute toxicity,dermal (category 5) skin irritation (category 2) eye irritation (category 2a) skin sensitization (category 1) acute aquatic toxicity (category 1) h226, h315, h319, h332, h335 p210,p233,p240,p241,p242 …

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